Like other countries, one of the most common diseases in Poland is cancer. In this regard, it is critical to make progress in understanding the mechanisms of cancer development and its progression. Considerable effort has been made in the past 40 years to understand the factors that trigger the disease so that it can be treated and ideally prevented. With our expertise in the field of cancer biology with focus on epigenetic gene regulation, my group at Institute of Genetics and Animal Breeding the Polish Academy of Sciences is one of the very few laboratories in Poland that are uniquely positioned to make exciting new contributions to this field of study. Disruption of epigenetic processes can lead to altered gene function and malignant cellular transformation. Our research mission is to prove that the epigenetic and transcriptional regulation play essential roles in regulating cancer driver genes through epigenetic mechanisms. Moreover, tissue engineering and cell therapy hold great promise clinically. MSCs, adipocyte-derived stem cells (ASCs) can be isolated from fat with very easy technique and will be amplified under many cell culture conditions. As such, it is considered a highly useful experimental and medical tools in the field of regenerative medicine. We are especially interested in the role of noncoding RNAs, transcriptional factors, and epigenetic regulators in controlling the capacity of differentiation of ASCs to multiple cell types as well as the beneficial use of ASCs in reproduction field.